CTGF anticorps

N° du produit ABIN641070

Détail du produit anti-CTGF anticorps

Antigène: CTGF (Connective Tissue Growth Factor (CTGF))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTGF est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func)

Fonction: Rabbit Anti-Human CTGF

Specificité: DS-PB-02576 specifically recognizes human CTGF (connective tissue growth factor), a 323 amino acid polypeptide and member of the CCN family of secreted cysteine rich regulatory proteins, which is produced by vascular endothelial and umbilical vein cells, and interacts with several other growth factors, including transforming growth factor beta (TGF-beta), vascular endothelial growth factor (VEGF) and bone morphogenetic proteins (BMPs). CTGF is a heparin-binding pleiotropic growth factor involved in chondrogenesis and potentially skeletogenesis. CTGF promotes the adhesion of epithelial cells and fibroblasts, stimulates integrin expression, and also promotes endothelial cell survival, migration and adhesion, implicating CTGF in angiogenesis. CTGF induces extracellular matrix formation, including the deposition of excessive collagen in fibrotic diseases, and has also been implicated in wound healing.

Attributs du produit: Cytokines/Chemokines/Growth Factors/Receptors

Purification: Purified

Immunogène: Antisera to human CTGF were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.

Isotype: IgG

Information d'application

Indications d'application: ELISA (dilution: 0.1, 0.2 μg/mL), Functional Assays, Immunofluorescence, Immunohistology - Paraffin, Western Blotting

Restrictions: For Research Use only

Stockage

Reconstitution: Reconstitute with 0.1 mL distilled water. For long term storage the addition of 0.09 % sodium azide is recommended. NB: For functional studies do not add azide.

Concentration: IgG concentration 1.0 mg/ml

Buffer: Phosphate buffered saline pH7.2

Stock: -20 °C

Stockage commentaire: -20°C

Détails sur CTGF

Antigène: CTGF (Connective Tissue Growth Factor (CTGF))

Autre désignation: CTGF (CTGF Produits)

Synonymes: anticorps Ccn2, anticorps Fisp12, anticorps Hcs24, anticorps fisp-12, anticorps CCN2, anticorps HCS24, anticorps IGFBP8, anticorps NOV2, anticorps CTGRP, anticorps ctgf, anticorps hm:zeh1559, anticorps si:dkey-266k12.4, anticorps wu:fl25c03, anticorps zeh1559, anticorps zgc:136644, anticorps XCTGF, anticorps ccn2, anticorps nov2, anticorps hcs24, anticorps igfbp8, anticorps CTGF, anticorps si:ch211-173b8.2, anticorps connective tissue growth factor, anticorps connective tissue growth factor a, anticorps connective tissue growth factor L homeolog, anticorps connective tissue growth factor b, anticorps Ctgf, anticorps CTGF, anticorps ctgfa, anticorps ctgf.L, anticorps ctgf, anticorps ctgfb

Pathways: Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Growth Factor Binding