Vimentin anticorps (Biotin)

N° du produit ABIN645826

Détail du produit anti-Vimentin anticorps (Biotin)

Antigène: Vimentin (VIM)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Vimentin est conjugé à/à la Biotin

Application: Immunohistochemistry (IHC)

Fonction: Mouse Anti-Human Vimentin, Biotinylated

Réactivité croisée (Details): Vimentin antibody will recognize most mammalian Vimentin except mouse and rat.

Attributs du produit: Collagen & Extracellular Matrix Proteins

Immunogène: Purified Human Vimentin.

Isotype: IgG1

Information d'application

Indications d'application: Immunohistochemistry.< div class='ty-product-feature'>< div class='ty-product-feature__label'>Cross Reactivity< div class='ty-product-feature__value'>Vimentin antibody will recognize most mammalian Vimentin except mouse and rat.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

Concentration: 1 mg/ml in PBS (after reconstitution).

Stock: -20 °C

Stockage commentaire: -20°C

Détails sur Vimentin

Antigène: Vimentin (VIM)

Autre désignation: Vimentin (VIM Produits)

Synonymes: anticorps CTRCT30, anticorps cb28, anticorps vime, anticorps vim, anticorps vim1, anticorps vim2, anticorps VIM, anticorps Vimentin, anticorps vim4, anticorps vimentin, anticorps vimentin L homeolog, anticorps vimentin S homeolog, anticorps VIM, anticorps Vim, anticorps vim, anticorps vim.L, anticorps vim.S

Sujet:

Target Description: Vimentin expression in human malignant glioma cells depends on cellular density, algorithms of drug delivery and chemo/radio treatment. Vimentin and detyrosinated microtubules provide structural support for the extensive microtentacles observed in detached tumor cells and a mechanism to promote successful metastatic spread. Primary colorectal carcinomas display aberrant expression of vimentin, and have activated Notch and TGFbeta signaling pathways. Vimentin is a strong arterial substrate for transglutaminases. Transglutaminase-mediated vimentin dimerization results in a novel unifying pathway by which vasodilatory and remodeling responses may be regulated. Ablation of vimentin expression inhibits migration and invasion of colon and breast cancer cell lines.< div class='ty-product-feature'>< div class='ty-product-feature__label'>Cross Reactivity< div class='ty-product-feature__value'>Vimentin antibody will recognize most mammalian Vimentin except mouse and rat.

Pathways: Caspase Cascade in Apoptosis