IL-8 anticorps (C-Term)

N° du produit ABIN652552

Cet anticorps Lapin Polyclonal détecte spécifiquement IL-8 dans WB, FACS, IHC (p) et IF. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour IL-8 anticorps (C-Term) (ABIN652552)

Antigène: IL-8 (IL8) (Interleukin 8 (IL8))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-8 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Clone: RB20676

Détail du produit anti-IL-8 anticorps

Épitope: AA 72-99, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This IL8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-99 amino acids from the C-terminal region of human IL8.

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-IL-8 (ABIN652552)

Shao, Lu, Zhang, Wang, Li, Hu, Wang, Lin: "Interleukin-8 upregulates integrin ?3 expression and promotes estrogen receptor-negative breast cancer cell invasion by activating the PI3K/Akt/NF-?B pathway." dans: Cancer letters, Vol. 364, Issue 2, pp. 165-72, (2015) (PubMed).

Bai, Tai, Li, Zhen, Gu, Jian, Wang, Lin, Zhao, Gong, Liang, Wang, Zhou: "Gankyrin activates IL-8 to promote hepatic metastasis of colorectal cancer." dans: Cancer research, Vol. 73, Issue 14, pp. 4548-58, (2013) (PubMed).

Détails sur IL-8

Antigène: IL-8 (IL8) (Interleukin 8 (IL8))

Autre désignation: IL8

Sujet: IL8 is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor.

Poids moléculaire: 11098

ID gène: 3576

NCBI Accession: NP_000575

UniProt: P10145

Pathways: Signalisation TLR, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagy