Angiotensin II Type-1 Receptor anticorps (AA 211-240)

N° du produit ABIN654078

Détail du produit anti-Angiotensin II Type-1 Receptor anticorps

Antigène: Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))

Épitope: AA 211-240

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Angiotensin II Type-1 Receptor est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Pig, Rb

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This AGTR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-240 amino acids from the Central region of human AGTR1.

Clone: RB19701

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:25. WB: 1:2000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur Angiotensin II Type-1 Receptor

Antigène: Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))

Autre désignation: AGTR1 (AGTR1 Produits)

Synonymes: anticorps AG2S, anticorps AGTR1A, anticorps AGTR1B, anticorps AT1, anticorps AT1AR, anticorps AT1B, anticorps AT1BR, anticorps AT1R, anticorps AT2R1, anticorps AT2R1A, anticorps AT2R1B, anticorps HAT1R, anticorps 1810074K20Rik, anticorps AI551199, anticorps AT1a, anticorps Agtr-1a, anticorps Agtr1, anticorps Angtr-1a, anticorps AT1A, anticorps XAT-1, anticorps agtr1-A, anticorps agtr1.2, anticorps AT1-R, anticorps at1, anticorps AGTR1, anticorps Agtr-1b, anticorps Angtr-1b, anticorps agtr1, anticorps agtr1-a, anticorps agtr1-b, anticorps xAT, anticorps angiotensin II receptor type 1, anticorps angiotensin II receptor, type 1a, anticorps angiotensin II receptor type 1 S homeolog, anticorps uncharacterized AGTR1, anticorps angiotensin II receptor, type 1b, anticorps angiotensin II receptor type 1 L homeolog, anticorps AGTR1, anticorps Agtr1a, anticorps agtr1.S, anticorps Agtr1, anticorps Agtr1b, anticorps agtr1.L

Sujet: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed, however, it is now believed that there is only one type 1 receptor gene in humans. At least five transcript variants have been described for this gene. Additional variants have been described but their full-length nature has not been determined. The entire coding sequence is contained in the terminal exon and is present in all transcript variants. [provided by RefSeq].

Poids moléculaire: 41061

ID gène: 185

NCBI Accession: NP_000676, NP_033611

UniProt: P30556

Pathways: Signalistation JAK/STAT, ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour