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STARD6 anticorps (C-Term)

STARD6 Reactivité: Humain WB, FACS Hôte: Lapin Polyclonal RB29820 unconjugated
N° du produit ABIN655777
  • Antigène Voir toutes STARD6 Anticorps
    STARD6 (StAR-Related Lipid Transfer (START) Domain Containing 6 (STARD6))
    Épitope
    • 7
    • 7
    • 7
    • 1
    AA 187-215, C-Term
    Reactivité
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 15
    Lapin
    Clonalité
    • 15
    Polyclonal
    Conjugué
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp STARD6 est non-conjugé
    Application
    • 15
    • 12
    • 12
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This STARD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-215 amino acids from the C-terminal region of human STARD6.
    Clone
    RB29820
    Isotype
    Ig Fraction
  • Indications d'application
    WB: 1:1000. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • LaVoie, Whitfield, Shi, King, Bose, Hui: "STARD6 is expressed in steroidogenic cells of the ovary and can enhance de novo steroidogenesis." dans: Experimental biology and medicine (Maywood, N.J.), Vol. 239, Issue 4, pp. 430-5, (2014) (PubMed).

  • Antigène
    STARD6 (StAR-Related Lipid Transfer (START) Domain Containing 6 (STARD6))
    Autre désignation
    STARD6 (STARD6 Produits)
    Synonymes
    anticorps 1700011K09Rik, anticorps 4833424I06Rik, anticorps 4933429L05Rik, anticorps AI644424, anticorps StAR related lipid transfer domain containing 6, anticorps StAR-related lipid transfer (START) domain containing 6, anticorps STARD6, anticorps Stard6
    Sujet
    Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1, MIM 184756) and by liver X receptors (e.g., LXRA, MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR, MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD6 (Soccio et al., 2002 [PubMed 12011452]).
    ID gène
    147323
    NCBI Accession
    NP_631910
    UniProt
    P59095
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