COL11A2 anticorps

N° du produit ABIN6566947

Détail du produit anti-COL11A2 anticorps

Antigène: COL11A2 (Collagen, Type XI, alpha 2 (COL11A2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COL11A2 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human COL11A2

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur COL11A2

Antigène: COL11A2 (Collagen, Type XI, alpha 2 (COL11A2))

Autre désignation: COL11A2 (COL11A2 Produits)

Synonymes: anticorps col11a2, anticorps MGC89039, anticorps COL11A2, anticorps RING3, anticorps DFNA13, anticorps DFNB53, anticorps FBCG2, anticorps HKE5, anticorps PARP, anticorps STL3, anticorps collagen, type XI, alpha 2, anticorps collagen type XI alpha 2 chain, anticorps bromodomain containing 2, anticorps col11a2, anticorps COL11A2, anticorps BRD2, anticorps Col11a2

Sujet:

Synonyms: COBA2,COL11A2,Collagen alpha 2(XI),Collagen alpha-2(XI) chain,Collagen type XI alpha 2,Collagen XI a2,DAQB-79P13.8,DFNA13,DFNB53,FBCG2,HGNC:2187,HKE5,PARP,Pro a2 chain of collagen type XI,STL3

Background: This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6.

Poids moléculaire:

Observed_MW: 150kDa

Calculated_MW: 31kDa/159-171kDa

ID gène: 1302

UniProt: P13942

Pathways: Signalisation RTK, Sensory Perception of Sound, Chromatin Binding