Spartan anticorps
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- Antigène Tous les produits Spartan (C1orf124)
- Spartan (C1orf124) (Chromosome 1 Open Reading Frame 124 (C1orf124))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Spartan est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of human SPRTN
- Isotype
- IgG
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- Indications d'application
- WB 1:500 - 1:2000
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- Spartan (C1orf124) (Chromosome 1 Open Reading Frame 124 (C1orf124))
- Autre désignation
- SPRTN (C1orf124 Produits)
- Synonymes
- anticorps Spartan, anticorps c1orf124, anticorps C1orf124, anticorps DDDL1880, anticorps DVC1, anticorps PRO4323, anticorps dJ876B10.3, anticorps C28H1orf124, anticorps SprT-like N-terminal domain, anticorps sprtn, anticorps SPRTN
- Sujet
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Synonyms: C1orf124,CA124,Chromosome 1 open reading frame 124 ,DDDL1880,dJ876B10.3,PRO4323,RP5-876B10.3,Spartan,SprT-like domain at the N terminus,SprT-like N-terminal domain,Zinc finger RAD18 domain-containing protein C1orf124
Background: The protein encoded by this gene may play a role in DNA repair during replication of damaged DNA. This protein recruits valosin containing protein (p97) to stalled DNA replication forks where it may prevent excessive translesional DNA synthesis and limit the number of DNA-damage induced mutations. It may also be involved in replication-related G2/M-checkpoint regulation. Deficiency of a similar protein in mouse causes chromosomal instability and progeroid phenotypes. Mutations in this gene have been associated with Ruijs-Aalfs syndrome (RJALS). Alternatively spliced transcript variants have been identified.
- Poids moléculaire
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Observed_MW: 60kDa
Calculated_MW: 24kDa/29kDa/55kDa
- ID gène
- 83932
- UniProt
- Q9H040
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