MBTPS1 anticorps
-
- Antigène Voir toutes MBTPS1 Anticorps
- MBTPS1 (Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1))
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp MBTPS1 est non-conjugé
-
Application
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein of human MBTPS1 (NP_003782.1).
- Isotype
- IgG
- Top Product
- Discover our top product MBTPS1 Anticorps primaire
-
-
- Indications d'application
- IHC 1:50-1:200 IF 1:50-1:200
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Antigène
- MBTPS1 (Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1))
- Autre désignation
- MBTPS1 (MBTPS1 Produits)
- Synonymes
- anticorps PCSK8, anticorps S1P, anticorps SKI-1, anticorps 0610038M03Rik, anticorps AV003995, anticorps Ski1, anticorps mKIAA0091, anticorps S1p, anticorps Ski-1, anticorps membrane bound transcription factor peptidase, site 1, anticorps membrane-bound transcription factor peptidase, site 1, anticorps MBTPS1, anticorps Mbtps1
- Sujet
- This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction.
- Poids moléculaire
-
Calculated_MW: 117kDa
- ID gène
- 8720
- UniProt
- Q14703
- Pathways
- ER-Nucleus Signaling
-