PSMC5 anticorps

N° du produit ABIN5967123

Détail du produit anti-PSMC5 anticorps

Antigène: PSMC5 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 5 (PSMC5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMC5 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human PSMC5 (NP_002796.4).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PSMC5

Antigène: PSMC5 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 5 (PSMC5))

Autre désignation: PSMC5 (PSMC5 Produits)

Synonymes: anticorps mSUG1, anticorps S8, anticorps SUG-1, anticorps SUG1, anticorps TBP10, anticorps TRIP1, anticorps p45, anticorps p45/SUG, anticorps wu:fa14g03, anticorps wu:fb23a11, anticorps zgc:92464, anticorps sug-1, anticorps sug1, anticorps tbp10, anticorps Sug1, anticorps PSMC5, anticorps xsug1, anticorps protease (prosome, macropain) 26S subunit, ATPase 5, anticorps proteasome 26S subunit, ATPase 5, anticorps proteasome 26S subunit, ATPase 5 L homeolog, anticorps proteasome 26S subunit, ATPase 5 S homeolog, anticorps Psmc5, anticorps PSMC5, anticorps psmc5, anticorps psmc5.L, anticorps psmc5.S

Sujet: PSMC5,S8,SUG-1,SUG1,TBP10,TRIP1,p45,p45/SUG,ATPase 5,The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha. Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire:

Observed_MW: 46kDa

Calculated_MW: 44kDa/45kDa

ID gène: 5705

UniProt: P62195

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway