OPTN anticorps

N° du produit ABIN5963871

Détail du produit anti-OPTN anticorps

Antigène: OPTN (Optineurin (OPTN))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OPTN est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human OPTN

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur OPTN

Antigène: OPTN (Optineurin (OPTN))

Autre désignation: OPTN (OPTN Produits)

Synonymes: anticorps nrp, anticorps fip2, anticorps hip7, anticorps hypl, anticorps glc1e, anticorps tfiiia-intp, anticorps ALS12, anticorps FIP2, anticorps GLC1E, anticorps HIP7, anticorps HYPL, anticorps NRP, anticorps TFIIIA-INTP, anticorps Fip2, anticorps 4930441O07Rik, anticorps fj52f04, anticorps si:ch211-240l19.3, anticorps wu:fj52f04, anticorps zgc:66386, anticorps zgc:77868, anticorps optineurin, anticorps optineurin L homeolog, anticorps OPTN, anticorps optn, anticorps Optn, anticorps optn.L

Sujet:

Synonyms: 14.7K interacting protein,Ag9 C5,ALS12,E3 14.7K interacting protein,E3-14.7K-interacting protein,FIP 2,FIP-2,FIP2,Glaucoma 1 open angle E (adult onset),Glaucoma 1 open angle E,GLC1E,HIP 7,HIP-7,HIP7,Huntingtin interacting protein 7,Huntingtin interacting protein HYPL,Huntingtin interacting protein L,Huntingtin yeast partner L,Huntingtin-interacting protein 7,Huntingtin-interacting protein L,HYPL,Injury inducible protein I 55,NEMO related protein,NEMO-related protein,NRP,Optic neuropathy inducing protein,Optic neuropathy-inducing protein,Optineurin,OPTN,OPTN,TFIIIA IntP,TFIIIA-IntP,Transcription factor IIIA interacting protein,Transcription factor IIIA-interacting protein,Tumor necrosis factor alpha inducible cellular protein containing leucine zipper domains

Background: This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.

Poids moléculaire:

Observed_MW: 78kDa

Calculated_MW: 59kDa/65kDa

ID gène: 10133

UniProt: Q96CV9

Pathways: M Phase