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Uromodulin anticorps

UMOD Reactivité: Humain, Souris WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5964310
  • Antigène Voir toutes Uromodulin (UMOD) Anticorps
    Uromodulin (UMOD)
    Reactivité
    • 55
    • 24
    • 21
    • 14
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain, Souris
    Hôte
    • 45
    • 12
    • 6
    • 2
    Lapin
    Clonalité
    • 55
    • 10
    Polyclonal
    Conjugué
    • 33
    • 9
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Uromodulin est non-conjugé
    Application
    • 54
    • 26
    • 22
    • 16
    • 14
    • 13
    • 13
    • 11
    • 9
    • 8
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Affinity purification
    Immunogène
    Recombinant protein of human UMOD
    Isotype
    IgG
    Top Product
    Discover our top product UMOD Anticorps primaire
  • Indications d'application
    WB 1:500 - 1:2000
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    Uromodulin (UMOD)
    Autre désignation
    UMOD (UMOD Produits)
    Synonymes
    anticorps ADMCKD2, anticorps FJHN, anticorps HNFJ, anticorps HNFJ1, anticorps MCKD2, anticorps THGP, anticorps THP, anticorps urehr4, anticorps uromodulin, anticorps UMOD, anticorps Umod
    Sujet

    Synonyms: ADMCKD2,FJHN,HNFJ,HNFJ1,MCKD2,medullary cystic kidney disease 2 (autosomal dominant),Tamm Horsfall glycoprotein,Tamm Horsfall urinary glycoprotein,Tamm-Horsfall urinary glycoprotein,THGP,THP,Umod,Urehd1,urehr4,UROM,uromodulin (uromucoid,Tamm-Horsfall glycoprotein),Uromodulin,Uromodulin,secreted form

    Background: The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants.

    Poids moléculaire

    Observed_MW: 70kDa

    Calculated_MW: 55kDa/66kDa/67kDa/69kDa/73kDa

    ID gène
    7369
    UniProt
    P07911
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