NCOR1 anticorps

N° du produit ABIN6570881

Détail du produit anti-NCOR1 anticorps

Antigène: NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCOR1 est non-conjugé

Application: Immunofluorescence (IF)

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human NCOR1 (NP_006302.2).

Isotype: IgG

Information d'application

Indications d'application: IF 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NCOR1

Antigène: NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

Autre désignation: NCOR1 (NCOR1 Produits)

Synonymes: anticorps ncor, anticorps zgc:56355, anticorps 5730405M06Rik, anticorps A230020K14Rik, anticorps N-CoR, anticorps RIP13, anticorps Rxrip13, anticorps mKIAA1047, anticorps N-CoR1, anticorps TRAC1, anticorps hN-CoR, anticorps nuclear receptor corepressor 1, anticorps nuclear receptor co-repressor 1, anticorps nuclear receptor corepressor 1 pseudogene, anticorps nuclear receptor corepressor 1 S homeolog, anticorps ncor1, anticorps NCOR1, anticorps CpipJ_CPIJ002507, anticorps LOC100343278, anticorps Ncor1, anticorps ncor1.S

Sujet: This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.

Poids moléculaire:

Observed_MW: 320kDa

Calculated_MW: 103kDa/258kDa/270kDa

ID gène: 9611

UniProt: O75376

Pathways: Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process