IDH2 anticorps

N° du produit ABIN6570980

Détail du produit anti-IDH2 anticorps

Antigène: IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IDH2 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human IDH2 (NP_002159.2).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200 IF 1:20-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur IDH2

Antigène: IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))

Autre désignation: IDH2 (IDH2 Produits)

Synonymes: anticorps F6P23.14, anticorps F6P23_14, anticorps IDH-II, anticorps NAD+ DEPENDENT ISOCITRATE DEHYDROGENASE SUBUNIT 2, anticorps isocitrate dehydrogenase II, anticorps isocitrate dehydrogenase subunit 2, anticorps D2HGA2, anticorps ICD-M, anticorps IDH, anticorps IDHM, anticorps IDP, anticorps IDPM, anticorps mNADP-IDH, anticorps E430004F23, anticorps IDPm, anticorps Idh-2, anticorps wu:fb33c06, anticorps wu:fk31e05, anticorps wu:fq43b01, anticorps zgc:55485, anticorps idh2, anticorps IDH2, anticorps isocitrate dehydrogenase subunit 2, anticorps isocitrate dehydrogenase (NADP(+)) 2, mitochondrial, anticorps isocitrate dehydrogenase 2 (NADP+), mitochondrial, anticorps isocitrate dehydrogenase 2 (NADP+), mitochondrial S homeolog, anticorps isocitrate dehydrogenase [NADP], mitochondrial, anticorps IDH2, anticorps Idh2, anticorps idh2.S, anticorps idh2, anticorps LOC100441867

Sujet: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.

Poids moléculaire:

Observed_MW: 51kDa

Calculated_MW: 45kDa/50kDa

ID gène: 3418

UniProt: P48735

Pathways: L'effet Warburg