UIMC1 anticorps

N° du produit ABIN6571014

Détail du produit anti-UIMC1 anticorps

Antigène: UIMC1 (Ubiquitin Interaction Motif Containing 1 (UIMC1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UIMC1 est non-conjugé

Application: Immunofluorescence (IF)

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human UIMC1 (NP_057374.3).

Isotype: IgG

Information d'application

Indications d'application: IF 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur UIMC1

Antigène: UIMC1 (Ubiquitin Interaction Motif Containing 1 (UIMC1))

Autre désignation: UIMC1 (UIMC1 Produits)

Synonymes: anticorps UIMC1, anticorps RAP80, anticorps X2HRIP110, anticorps 9430016E08Rik, anticorps D330018D10Rik, anticorps D630032M02Rik, anticorps RIP110, anticorps Rxrip110, anticorps RGD1307009, anticorps ubiquitin interaction motif containing 1, anticorps UIMC1, anticorps Uimc1

Sujet: This gene encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions. This protein binds ubiquitinated lysine 63 of histone H2A and H2AX. This protein may also function as a repressor of transcription. Alternative splicing results in multiple transcript variants.

Poids moléculaire:

Observed_MW: 120kDa, 80kDa, 60kDa

Calculated_MW: 17kDa/38kDa/61kDa/70kDa/79kDa

ID gène: 51720

UniProt: Q96RL1

Pathways: Réparation de l'ADN, Nuclear Hormone Receptor Binding, Positive Regulation of Response to DNA Damage Stimulus