SNAP91 anticorps

N° du produit ABIN5967842

Détail du produit anti-SNAP91 anticorps

Antigène: SNAP91 (Synaptosomal-Associated Protein 91 (SNAP91))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNAP91 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human CALM2

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SNAP91

Antigène: SNAP91 (Synaptosomal-Associated Protein 91 (SNAP91))

Autre désignation: CALM (SNAP91 Produits)

Synonymes: anticorps AP180, anticorps CALM, anticorps Ap180, anticorps 91kDa, anticorps F1-20, anticorps mKIAA0656, anticorps synaptosome associated protein 91, anticorps synaptosomal-associated protein, 91kDa homolog, anticorps synaptosomal-associated protein 91, anticorps SNAP91, anticorps LOC100147907, anticorps Snap91

Sujet:

Synonyms: CALM 1,CALM 2,CALM 3,CALM,CALM,CALM1,CALM2,Calm3,CALML2,calmodulin 1 (phosphorylase kinase,delta),Calmodulin 2 (phosphorylase kinase,delta),Calmodulin 3 (phosphorylase kinase,delta),Calmodulin,CaM,CAM I,CAM1,CAM2,CAM3,CAMB,CAMC,CAMI,CAMII,CPVT4,DD132,FLJ99410,LP7057 protein,PHKD,PHKD2,PHKD3,phosphorylase kinase delta,phosphorylase kinase,delta subunit

Background: This gene is a member of the calmodulin gene family. There are three distinct calmodulin genes dispersed throughout the genome that encode the identical protein, but differ at the nucleotide level. Calmodulin is a calcium binding protein that plays a role in signaling pathways, cell cycle progression and proliferation. Several infants with severe forms of long-QT syndrome (LQTS) who displayed life-threatening ventricular arrhythmias together with delayed neurodevelopment and epilepsy were found to have mutations in either this gene or another member of the calmodulin gene family (PMID:23388215). Mutations in this gene have also been identified in patients with less severe forms of LQTS (PMID:24917665), while mutations in another calmodulin gene family member have been associated with catecholaminergic polymorphic ventricular tachycardia (CPVT)(PMID:23040497), a rare disorder thought to be the cause of a significant fraction of sudden cardiac deaths in young individuals. Pseudogenes of this gene are found on chromosomes 10, 13, and 17. Alternative splicing results in multiple transcript variants encoding different isoforms.

Poids moléculaire:

Observed_MW: 15kDa

Calculated_MW: 17kDa

ID gène: 801

UniProt: P62158