APITD1 anticorps

N° du produit ABIN6571658

Détail du produit anti-APITD1 anticorps

Antigène: APITD1 (Apoptosis-Inducing, TAF9-Like Domain 1 (APITD1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APITD1 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human APITD1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur APITD1

Antigène: APITD1 (Apoptosis-Inducing, TAF9-Like Domain 1 (APITD1))

Autre désignation: APITD1 (APITD1 Produits)

Synonymes: anticorps CENP-S, anticorps CENPS, anticorps FAAP16, anticorps MHF1, anticorps 2610040C18Rik, anticorps 2810407L01Rik, anticorps cenps, anticorps mhf1, anticorps APITD1, anticorps Apitd1, anticorps Mhf1, anticorps apitd1, anticorps zgc:194319, anticorps centromere protein S, anticorps apoptosis-inducing, TAF9-like domain 1, anticorps centromere protein S L homeolog, anticorps CENPS, anticorps Cenps, anticorps cenps.L, anticorps APITD1, anticorps cenps

Sujet:

Synonyms: APITD1,Apoptosis-inducing TAF9-like domain-containing protein 1,apoptosis-inducing, TAF9-like domain 1,CENP-S,CENPS,CENPS,Centromere protein S,FAAP16,FANCM-interacting histone fold protein 1,Fanconi anemia-associated polypeptide of 16 kDa,MGC32686,MHF 1

Background: This gene was identified in the neuroblastoma tumor suppressor candidate region on chromosome 1p36. It contains a TFIID-31 domain, similar to that found in TATA box-binding protein-associated factor, TAF(II)31, which is required for p53-mediated transcription activation. This gene was expressed at very low levels in neuroblastoma tumors, and was shown to reduce cell growth in neuroblastoma cells, suggesting that it may have a role in a cell death pathway. The protein is a component of multiple complexes, including the Fanconi anemia (FA) core complex, the APITD1/CENPS complex, and the CENPA-CAD (nucleosome distal) complex. Known functions include an involvement with chromatin associations of the FA core complex, and a role in the stable assembly of the outer kinetochore. Alternative splicing of this gene results in multiple transcript variants. Naturally occurring read-through transcripts also exist between this gene and the downstream cortistatin (CORT) gene, as represented in GeneID:100526739. An APITD1-related pseudogene has been identified on chromosome 7.

Poids moléculaire:

Observed_MW: 16kDa

Calculated_MW: 9kDa/15kDa/19kDa

ID gène: 100526739

UniProt: Q8N2Z9