TAX1BP3 anticorps

N° du produit ABIN6571899

Détail du produit anti-TAX1BP3 anticorps

Antigène: TAX1BP3 (Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein 3 (TAX1BP3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TAX1BP3 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human TAX1BP3

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TAX1BP3

Antigène: TAX1BP3 (Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein 3 (TAX1BP3))

Autre désignation: TAX1BP3 (TAX1BP3 Produits)

Synonymes: anticorps TIP-1, anticorps 1300011C24Rik, anticorps RP23-263M10.10, anticorps tax1bp3, anticorps wu:fb37e03, anticorps wu:fc23g08, anticorps zgc:55513, anticorps Tax1 binding protein 3, anticorps Tax1 (human T cell leukemia virus type I) binding protein 3, anticorps Tax1 (human T-cell leukemia virus type I) binding protein 3 S homeolog, anticorps Tax1 (human T-cell leukemia virus type I) binding protein 3, anticorps TAX1BP3, anticorps Tax1bp3, anticorps tax1bp3.S, anticorps tax1bp3

Sujet:

Synonyms: Glutaminase interacting protein 3,Glutaminase-interacting protein 3,Tax interaction protein 1,Tax1 (human T cell leukemia virus type I) binding protein 3,Tax1 binding protein 3,Tax1-binding protein 3,Tax1bp3,TIP 1,TIP-1,TIP1,TX1B3

Background: This gene encodes a small, highly conserved protein with a single PDZ domain. PDZ (PSD-95/Discs large/ZO-1 homologous) domains promote protein-protein interactions that affect cell signaling, adhesion, protein scaffolding, and receptor and ion transporter functions. The encoded protein interacts with a large number of target proteins that play roles in signaling pathways, for example, it interacts with Rho A and glutaminase L and also acts as a negative regulator of the Wnt/beta-catenin signaling pathway. This protein was first identified as binding to the T-cell leukaemia virus (HTLV1) Tax oncoprotein. Overexpression of this gene has been implicated in altered cancer cell adhesion, migration and metastasis. The encoded protein also modulates the localization and density of inwardly rectifying potassium channel 2.3 (Kir2.3). To date, this protein has been shown to play a role in cell proliferation, development, stress response, and polarization. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Poids moléculaire:

Observed_MW: 14kDa

Calculated_MW: 13kDa

ID gène: 30851

UniProt: O14907

Pathways: Monocarboxylic Acid Catabolic Process