Mre11 anticorps (AA 182-582)

N° du produit ABIN190284

Cet anticorps anti-Mre11 Monoclonal Souris (Clone 12D7) (ABIN190284) détecte spécifiquement Mre11 dans WB, ELISA, IP, IHC (p), IF/ICC, Func et PLA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Mre11 anticorps (AA 182-582) (ABIN190284)

Antigène: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Mre11 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (fixed cells) (IF/ICC), Functional Studies (Func), Proximity Ligation Assay (PLA)

Clone: 12D7

Détail du produit anti-Mre11 anticorps

Épitope: AA 182-582

Fonction: Anti-Mre11 Mouse Monoclonal Antibody

Specificité: This antibody recognizes human, mouse, and rat Mre11.

Réactivité croisée: Humain

Immunogène: GST fusion protein corresponding to aa 182-582 of Mre11.

Isotype: IgG1

Information d'application

Indications d'application: Immunoblotting: Use at 0.5-2 μg/mL. A band of ~80 kDa is detected. Detection of Mre11 in 30 μg of whole cell extracts.
Immunofluorescence: use at 1-5 μg/mL. Detection of Mre11 in HeLa cells fixed in 4 % paraformaldehyde for 15 minutes.
These are recommended concentrations.
Endusers should determine optimal concentrations for their applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: Dilute in PBS or medium which is identical to that used in the assay system.

Concentration: Lot specific

Buffer: PBS, pH 7.4

Stock: -20 °C,-80 °C

Stockage commentaire: This antibody is stable for at least one (1) year at -20°C to-70°C. Store as concentrated solution in appropriate aliquots to avoid multiple freeze-thaw cycles.

Détails sur Mre11

Antigène: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Autre désignation: MRE11

Sujet: Double-strand break repair protein MRE11,Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA rPubMed:10888888, PubMed:11741547, PubMed:15064416, PubMed:29670289, PubMed:30612738, PubMed:9590181, PubMed:9705271}.,Nucleus, Chromosome, telomere, Chromosome,EC 3.1.-.-, Double-strand break repair protein MRE11A, Meiotic recombination 11 homolog 1, MRE11 homolog 1, Meiotic recombination 11 homolog A, MRE11 homolog A

UniProt: P49959

Pathways: Réparation de l'ADN