Grancalcin anticorps (AA 42-217)

N° du produit ABIN6654161

Détail du produit anti-Grancalcin anticorps

Antigène: Grancalcin (GCA) (Grancalcin, EF-Hand Calcium Binding Protein (GCA))

Épitope: AA 42-217

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Grancalcin est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antigen affinity purified

Immunogène: Amino acids A42-I217 from the human protein were used as the immunogen for the Grancalcin antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Grancalcin antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Direct ELISA: 0.1-0.5 μg/mL (human recombinant protein)

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Grancalcin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur Grancalcin

Antigène: Grancalcin (GCA) (Grancalcin, EF-Hand Calcium Binding Protein (GCA))

Autre désignation: Grancalcin / GCA (GCA Produits)

Synonymes: anticorps Grancalcin, anticorps 5133401E04Rik, anticorps AI573844, anticorps GCL, anticorps zgc:92027, anticorps grancalcin, anticorps Grancalcin, anticorps zgc:92027, anticorps GCA, anticorps gran, anticorps LOC100280890, anticorps Gca

Sujet: Grancalcin is a protein that in humans is encoded by the GCA gene. This gene is mapped to 2q24.2. This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction, with magnesium alone, it partitions with the granule fraction, and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation.

UniProt: P28676