CD3 epsilon anticorps (PE)

N° du produit ABIN6655180

N° du produit (Fournisseur): 200-308-n12

L’anticorps anti-CD3 epsilon Monoclonal Souris est utilisé pour la détection de CD3 epsilon dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour CD3 epsilon anticorps (PE) (ABIN6655180)

Antigène: CD3 epsilon (CD3E)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD3 epsilon est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: HIT3a

Détail du produit anti-CD3 epsilon anticorps (PE)

N° du produit (Fournisseur): 200-308-n12

Fournisseur: Rockland

Fonction: CD3 Phycoerythrin Antibody

Réactivité croisée (Details): Reactivity is observed against human CD3.

Purification: Phycoerythrin conjugated CD3 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD3.

Stérilité: Sterile filtered

Immunogène: Anti-CD3 Antibody (Monoclonal) was produced by repeated immunizations with CD3 antigen.

Isotype: IgG2a kappa

Labeling Ratio: 1-2

Information d'application

Indications d'application: Optional[Neutralization_Dilution]: 5 uL/test/1x10e5 to 1x10e8 cells

Commentaires:

Anti-CD3 is tested for Flow Cytometry. Researchers should determine optimal titers for applications that are not stated.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 0.1 % Gelatin

Preservative: 0.09 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.

Date de péremption: 6 months

Détails sur CD3 epsilon

Antigène: CD3 epsilon (CD3E)

Autre désignation: CD3E

Sujet:

Synonyms: T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e

Background: The Hit3a antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor - CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing cell proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.The Hit3a antibody is a widely used phenotypic marker for human T cells. In addition, binding/cross-linking of Hit3a antibody to CD3e can induce cell activation. The antibody has also been demonstrated to be cross-reactive with Chimpanzee CD3.

Gene Name: CD3E

ID gène: 916

NCBI Accession: NP_000724

UniProt: P07766

Pathways: TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway