KCNQ4 anticorps (N-Term)

N° du produit ABIN6656738

Détail du produit anti-KCNQ4 anticorps

Antigène: KCNQ4 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4))

Épitope: N-Term

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KCNQ4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Fluorescence Microscopy (FM)

Réactivité croisée: Humain, Souris, Rat (Rattus)

Purification: Anti-KCNQ4 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with KCNQ4 from Human, Rat, and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity with KCNQ4 from other sources has not been determined. Channels and Transporters research.

Immunogène:

Immunogen: KCNQ4 Antibody was produced in mice by repeated immunizations raised against a fusion protein n-terminal region of human KCNQ4.

Immunogen Type: Peptide

Clone: S43-6

Isotype: IgG1

Information d'application

Indications d'application:

Immunohistochemistry Dilution: 0.1-1.0 μg/mL

Application Note: Anti-KCNQ4 Antibody is suitable for use in WB, IP, and IF microscopy. Expect a band approximately ~77 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Western Blot Dilution: 1-10 μg/mL

IF Microscopy Dilution: 1.0-10 μg/mL

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Stock: RT,4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Détails sur KCNQ4

Antigène: KCNQ4 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4))

Autre désignation: KCNQ4 (KCNQ4 Produits)

Synonymes: anticorps KCNQ4, anticorps k(v)7.4, anticorps kv7.4, anticorps DFNA2, anticorps DFNA2A, anticorps KV7.4, anticorps potassium voltage-gated channel subfamily Q member 4, anticorps potassium channel, voltage gated KQT-like subfamily Q, member 4, anticorps potassium voltage-gated channel, subfamily Q, member 4, anticorps KCNQ4, anticorps kcnq4, anticorps Kcnq4

Sujet:

Synonyms: DFNA2, KQT like 4, Kv7.4, voltage gated potassium channel subunit Kv7.4, IKs producing slow voltage-gated potassium channel subunit alpha, KvLQT4, KQT-like 4, Potassium voltage-gated channel subfamily KQT member 4

Background: Specifically, the protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anticonvulsant drug.

Gene Name: KCNQ4

ID gène: 9132

NCBI Accession: NP_004691

UniProt: P56696

Pathways: Sensory Perception of Sound