Tamalin/GRASP anticorps (C-Term)

N° du produit ABIN6658234

Détail du produit anti-Tamalin/GRASP anticorps

Antigène: Tamalin/GRASP (GRASP) (GRP1 (General Receptor For phosphoinositides 1)-Associated Scaffold Protein (GRASP))

Épitope: C-Term

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Tamalin/GRASP est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Souris, Rat (Rattus)

Réactivité croisée (Details): Cross reactivity with GRASP from other species has not been determined.

Purification: Anti-GRASP Antibody is directed against rat GRASP protein. The antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Expect reactivity with the following species based on sequence homology: bovine, canine, human, rat, and mouse.

Immunogène:

Immunogen: Anti-GRASP Antibody was produced by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region.

Immunogen Type: Peptide

Isotype: IgG

Information d'application

Indications d'application:

Application Note: Anti-GRASP (Rabbit) antibody is suitable for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 95 kDa in size corresponding to GRASP protein in the appropriate cell lysate or extract.

Western Blot Dilution: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Détails sur Tamalin/GRASP

Antigène: Tamalin/GRASP (GRASP) (GRP1 (General Receptor For phosphoinositides 1)-Associated Scaffold Protein (GRASP))

Autre désignation: GRASP (GRASP Produits)

Synonymes: anticorps GRASP, anticorps tamalin, anticorps TAMALIN, anticorps general receptor for phosphoinositides 1 associated scaffold protein, anticorps GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein, anticorps GRASP, anticorps grasp, anticorps Grasp

Sujet:

Synonyms: GRIP1-associated protein 1, Glutamate receptor-interacting protein 1, GRASP1

Background: GRASP Antibody detects GRASP protein. PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo. Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity. Therefore, GRASP antibody is ideal for investigators involved in neuronal plasticity and remodelling and more generally in Neuroscience.

Gene Name: GRIPAP1

ID gène: 116493

UniProt: P97879