PLG anticorps

N° du produit ABIN6719276

L’anticorps Lapin Polyclonal anti-PLG a été validé pour WB et FACS. Il convient pour détecter PLG dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PLG anticorps (ABIN6719276)

Antigène: PLG (Plasminogen (PLG))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLG est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-PLG anticorps

Fonction: Anti-Plasminogen/PLG Antibody Picoband®

Séquence: EPLDDYVNTQ GASLFSVTKK QL

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Plasminogen/PLG Antibody Picoband® (ABIN6719276). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human Plasminogen, which shares 72.7% amino acid (aa) sequence identity with both mouse and rat Plasminogen.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Forsgren, M., Raden, B., Israelsson, M., Larsson, K., Heden, L.-O. Molecular cloning and characterization of a full-length cDNA clone for human plasminogen. FEBS Lett. 213: 254-260, 1987. 2. Miyata, T., Iwanaga, S., Sakata, Y., Aoki, N. Plasminogen Tochigi: inactive plasmin resulting from replacement of alanine-600 by threonine in the active site. Proc. Nat. Acad. Sci. 79: 6132-6136, 1982.

Commentaires:

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur PLG

Antigène: PLG (Plasminogen (PLG))

Autre désignation: PLG

Sujet:

Synonyms: Plasminogen, Plasmin heavy chain A, Activation peptide, Angiostatin, Plasmin heavy chain A, short form, Plasmin light chain B, PLG

Tissue Specificity: Present in plasma and many other extracellular fluids. It is synthesized in the liver.

Background: Plasminogen (PLG) is a circulating zymogen that is converted to the active enzyme plasmin by cleavage of the peptide bond between arg560 and val561, which is mediated by urokinase (PLAU) and tissue plasminogen activator (PLAT). The main function of plasmin is to dissolve fibrin (see, e.g., FGA) clots. Plasmin, like trypsin, belongs to the family of serine proteinases. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis.

Poids moléculaire: 100 kDa

ID gène: 5340

UniProt: P00747

Pathways: Système du Complément, Lipid Metabolism