ERCC3 anticorps (AA 665-715)

N° du produit ABIN6719310

Détail du produit anti-ERCC3 anticorps

Antigène: ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))

Épitope: AA 665-715

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERCC3 est non-conjugé

Application: Western Blotting (WB), ELISA

Fonction: Rabbit IgG polyclonal antibody for XPB detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for XPB detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human XPB recombinant protein (Position: Q665-K715).

Isotype: IgG

Information d'application

Indications d'application:

Application details: Western blot|0.1-0.5 μg/mL Direct ELISA|0.1-0.5 μg/mL

Commentaires:

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur ERCC3

Antigène: ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))

Autre désignation: ERCC3 (ERCC3 Produits)

Synonymes: anticorps BTF2, anticorps GTF2H, anticorps RAD25, anticorps TFIIH, anticorps XPB, anticorps BTF2 p89, anticorps Ercc-3, anticorps wu:fc25f08, anticorps ERCC excision repair 3, TFIIH core complex helicase subunit, anticorps excision repair cross-complementing rodent repair deficiency, complementation group 3, anticorps excision repair cross-complementation group 3, anticorps ERCC3, anticorps Ercc3, anticorps ercc3

Sujet:

Synonyms: General transcription and DNA repair factor IIH helicase subunit XPB, TFIIH subunit XPB, Basic transcription factor 2 89 kDa subunit, BTF2 p89, DNA excision repair protein ERCC-3, DNA repair protein complementing XP-B cells, TFIIH basal transcription factor complex 89 kDa subunit, TFIIH 89 kDa subunit, TFIIH p89, Xeroderma pigmentosum group B-complementing protein, ERCC3, XPB, XPBC

Background: XPB (xeroderma pigmentosum type B) is an ATP-dependent DNA helicase in humans that is a part of the TFIIH transcription factor complex. This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants.

ID gène: 2071

UniProt: P19447

Pathways: Réparation de l'ADN