SLC11A1 anticorps (AA 183-549)
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- Antigène Voir toutes SLC11A1 Anticorps
- SLC11A1 (Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 1 (SLC11A1))
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Épitope
- AA 183-549
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SLC11A1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Fonction
- Rabbit IgG polyclonal antibody for NRAMP1/SLC11A1 detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.
- Réactivité croisée (Details)
- No cross reactivity with other proteins.
- Attributs du produit
- Rabbit IgG polyclonal antibody for NRAMP1/SLC11A1 detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.
- Purification
- Immunogen affinity purified.
- Immunogène
- E.coli-derived human NRAMP1/SLC11A1 recombinant protein (Position: F183-S549).
- Isotype
- IgG
- Top Product
- Discover our top product SLC11A1 Anticorps primaire
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- Indications d'application
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Application details: Western blot|0.1-0.5 μg/mL Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL Direct ELISA|0.1-0.5 μg/mL
- Commentaires
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Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Antigène
- SLC11A1 (Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 1 (SLC11A1))
- Autre désignation
- SLC11A1 (SLC11A1 Produits)
- Synonymes
- anticorps SLC11A1, anticorps NRAMP1, anticorps LSH, anticorps NRAMP, anticorps Bcg, anticorps Itg, anticorps Lsh, anticorps Nramp1, anticorps Ity, anticorps Nramp, anticorps ity, anticorps BCG, anticorps solute carrier family 11 member 1 L homeolog, anticorps solute carrier family 11 member 1, anticorps solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1, anticorps slc11a1.L, anticorps SLC11A1, anticorps Slc11a1
- Sujet
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Synonyms: Natural resistance-associated macrophage protein 1, NRAMP 1, Solute carrier family 11 member 1, SLC11A1, LSH, NRAMP, NRAMP1
Background: Natural resistance-associated macrophage protein 1 is a protein that in humans is encoded by the SLC11A1gene. It is mapped to 2q35. This gene is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and encodes a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in this gene have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn disease. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.
- ID gène
- 6556
- UniProt
- P49279
- Pathways
- Transition Metal Ion Homeostasis, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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