NOTCH3 anticorps (APC)

N° du produit ABIN6722240

L’anticorps Souris Monoclonal anti-NOTCH3 a été validé pour FACS. Il convient pour détecter NOTCH3 dans des échantillons de Humain.

Aperçu rapide pour NOTCH3 anticorps (APC) (ABIN6722240)

Antigène: NOTCH3 (Notch 3 (NOTCH3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NOTCH3 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Clone: MHN3-21

Détail du produit anti-NOTCH3 anticorps (APC)

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Détails sur NOTCH3

Antigène: NOTCH3 (Notch 3 (NOTCH3))

Autre désignation: Notch3

Sujet:

Synonyms: NOTCH3,Notch 3,Notch 3 extracellular truncation,Notch 3 intracellular domain

Background: The Notch receptors are highly conserved from invertebrates to mammals. While Notch 1 and Notch 2 exhibit the highest structural similarity among the four mammalian Notch receptors. Notch 3 has a number of structural and functional differences. The binding of Notch 3 to its ligands results in the proteolysis of Notch and movement of intracellular portions of Notch into the nucleus. This translocation triggers a series of signaling processes. Notch 3 is primarily expressed in adult arterial smooth muscle cells. Notch3 gene mutation can cause CADASIL, a hereditary early stroke syndrome.

ID gène: 4854

UniProt: Q9UM47

Pathways: Signalisation Notch