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CD3 epsilon anticorps (AA 101-189)

Cet anticorps anti-CD3 epsilon est un anticorps Lapin Polyclonal détectant CD3 epsilon dans FACS, WB, ELISA, IHC (fro), IHC (p) et IF (p). Adapté pour Humain, Souris et Rat. Ce Primary Antibody a été cité dans 3+ publications.
N° du produit ABIN672921

Aperçu rapide pour CD3 epsilon anticorps (AA 101-189) (ABIN672921)

Antigène

Voir toutes CD3 epsilon (CD3E) Anticorps
CD3 epsilon (CD3E)

Reactivité

  • 315
  • 206
  • 51
  • 42
  • 21
  • 19
  • 8
  • 8
  • 8
  • 7
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 200
  • 149
  • 47
  • 43
  • 23
  • 12
  • 2
  • 2
  • 1
  • 1
  • 1
Lapin

Clonalité

  • 357
  • 116
  • 7
Polyclonal

Conjugué

  • 165
  • 36
  • 35
  • 25
  • 23
  • 12
  • 11
  • 11
  • 11
  • 11
  • 11
  • 11
  • 8
  • 8
  • 7
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp CD3 epsilon est non-conjugé

Application

  • 352
  • 197
  • 153
  • 115
  • 109
  • 82
  • 44
  • 32
  • 26
  • 26
  • 23
  • 22
  • 21
  • 14
  • 13
  • 8
  • 6
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Épitope

    • 61
    • 41
    • 26
    • 16
    • 15
    • 14
    • 11
    • 9
    • 9
    • 8
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-189

     Réactivité croisée

    Humain, Souris, Rat

    Purification

    Purified by Protein A.

    Immunogène

    KLH conjugated synthetic peptide derived from mouse CD3 epsilon

    Isotype

    IgG
  • Indications d'application

    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Date de péremption

    12 months
  • Karaboga, Demirtas, Karaca: "Investigation of the relationship between the Th17/IL-23 pathway and innate-adaptive immune system in TNBS-induced colitis in rats." dans: Iranian journal of basic medical sciences, Vol. 20, Issue 8, pp. 870-879, (2017) (PubMed).

    Becher, Lindner, Fröhlich, Savvatis, Westermann, Tschöpe: "Assessment of cardiac inflammation and remodeling during the development of streptozotocin-induced diabetic cardiomyopathy in vivo: a time course analysis." dans: International journal of molecular medicine, Vol. 32, Issue 1, pp. 158-64, (2013) (PubMed).

  • Antigène

    CD3 epsilon (CD3E)

    Autre désignation

    CD3 epsilon

    Sujet

    Synonyms: CD3, T3e, AI54783, CD3epsilon, T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e

    Background: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008].

    ID gène

    12501

    UniProt

    P22646

    Pathways

    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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