NR1H4 anticorps (AA 194-243)

N° du produit ABIN214795

Détail du produit anti-NR1H4 anticorps

Antigène: NR1H4 (Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))

Épitope: AA 194-243

Reactivité: Humain, Rat, Souris, Chien, Cheval, Boeuf (Vache), Porc, Cobaye, Singe, Roussette (Chauve-souris)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NR1H4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marque: IHC-plus™

Specificité: Human NR1H4

Homologie: Percent identity by BLAST analysis: Human, Mouse, Rat, Dog, Bovine, Horse, Pig, Guinea pig (100%) Rabbit (92%) Chicken (85%).

Purification: Immunoaffinity purified

Immunogène: Synthetic peptide located between aa194-243 of human NR1H4 (Q96RI1-2, NP_005114). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Elephant, Dog, Bovine, Bat, Horse, Pig, Guinea pig (100%), Hamster, Rabbit (92%), Turkey, Chicken (85%), Platypus (84%), M. tuberculosis (83%).

Type of Immunogen: Synthetic peptide

Information d'application

Indications d'application: Approved: IHC, IHC-P (5 μg/mL), WB (0.2 - 1 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with 50 μL of distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Détails sur NR1H4

Antigène: NR1H4 (Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))

Autre désignation: NR1H4 / FXR (NR1H4 Produits)

Synonymes: anticorps zgc:110190, anticorps zgc:92742, anticorps NR1H4, anticorps BAR, anticorps FXR, anticorps HRR-1, anticorps HRR1, anticorps RIP14, anticorps AI957360, anticorps Fxr, anticorps Rxrip14, anticorps nuclear receptor subfamily 1, group H, member 5 S homeolog, anticorps nuclear receptor subfamily 1, group H, member 4, anticorps nuclear receptor subfamily 1 group H member 4, anticorps nr1h5.S, anticorps nr1h4, anticorps NR1H4, anticorps Nr1h4

Sujet: Name/Gene ID: NR1H4
Subfamily: NR1 Thyroid hormone-like
Family: NHR

Synonyms: NR1H4, BAR, Farnesyl x receptor, FXR, HRR1, Farnesoid x activated receptor, Farnesoid X receptor, Farnesol receptor HRR-1, HRR-1, RXR-interacting protein 14, RIP14, Bile acid receptor, Farnesoid X nuclear receptor, Farnesoid X-activated receptor

ID gène: 9971

NCBI Accession: NP_005114

UniProt: Q96RI1

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Carbohydrate Metabolic Process