OLR1 anticorps (AA 201-273) (FITC)
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- Antigène Voir toutes OLR1 Anticorps
- OLR1 (Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1))
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Épitope
- AA 201-273
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Reactivité
- Humain, Souris, Rat, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp OLR1 est conjugé à/à la FITC
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain, Souris, Lapin, Rat
- Homologie
- Cow
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from Rabbit LOX-1
- Isotype
- IgG
- Top Product
- Discover our top product OLR1 Anticorps primaire
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- Indications d'application
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- OLR1 (Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1))
- Autre désignation
- Lox 1 (OLR1 Produits)
- Synonymes
- anticorps OLR1, anticorps LOX1, anticorps Olr1, anticorps CLEC8A, anticorps LOXIN, anticorps SCARE1, anticorps SLOX1, anticorps LOX-1, anticorps SR-EI, anticorps Scare1, anticorps Oldlr1, anticorps Oldr1, anticorps PLOX-1, anticorps oxidized low density lipoprotein receptor 1, anticorps oxidized low density lipoprotein (lectin-like) receptor 1, anticorps OLR1, anticorps Olr1
- Sujet
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Synonyms: LOX1, LOX-1, Oxidized low-density lipoprotein receptor 1, Ox-LDL receptor 1, Lectin-like oxidized LDL receptor 1, Lectin-like oxLDL receptor 1, Lectin-type oxidized LDL receptor 1, OLR1
Background: Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria (By similarity).
- ID gène
- 100009322
- UniProt
- Q9XTA8
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