COL4a3 anticorps (AA 1571-1670) (HRP)

N° du produit ABIN678137

Détail du produit anti-COL4a3 anticorps (HRP)

Antigène: COL4a3 (COL4A3) (Collagen, Type IV, alpha 3 (COL4A3))

Épitope: AA 1571-1670

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COL4a3 est conjugé à/à la HRP

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris, Rat

Homologie: Human

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Tumstatin

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur COL4a3

Antigène: COL4a3 (COL4A3) (Collagen, Type IV, alpha 3 (COL4A3))

Autre désignation: Tumstatin (COL4A3 Produits)

Synonymes: anticorps zTumstatin, anticorps [a]3(IV), anticorps alpha3(IV), anticorps collagen type IV alpha 3 chain, anticorps collagen, type IV, alpha 3, anticorps COL4A3, anticorps col4a3, anticorps Col4a3

Sujet:

Synonyms: Collagen alpha-3IV chain, Alpha 3 type IV collagen, Alpha3 type IV collagen, COL4A 3, COL4A3, Collagen IV alpha 3 polypeptide, Collagen type IV alpha 3 Goodpasture antigen, Collagen type IV alpha 3, Goodpasture antigen, OTTHUMP00000195044, Tumstatin, Col4a3, CO4A3_HUMAN.

Background: COL4A3 (Collagen, type IV, alpha 3) belongs to the type IV collagen family. Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Type IV collagen is a multimeric protein composed of 3 alpha subunits. These subunits are encoded by 6 different genes, alpha 1 through alpha 6, each of which can form a triple helix structure with 2 other subunits to form type IV collagen. Tumstatin, a cleavage fragment corresponding to the collagen alpha 3(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity.

ID gène: 1285

Pathways: Sensory Perception of Sound, Positive Regulation of Endopeptidase Activity