PSMB8 anticorps (AA 171-272)

N° du produit ABIN680833

Détail du produit anti-PSMB8 anticorps

Antigène: PSMB8 (Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8))

Épitope: AA 171-272

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMB8 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Proteasome 20S LMP7

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur PSMB8

Antigène: PSMB8 (Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8))

Autre désignation: LMP7 (PSMB8 Produits)

Synonymes: anticorps ALDD, anticorps D6S216, anticorps D6S216E, anticorps JMP, anticorps LMP7, anticorps NKJO, anticorps PSMB5i, anticorps RING10, anticorps ATP6V0D2, anticorps lmp7, anticorps prosome, anticorps macropain, anticorps Lmp-7, anticorps Lmp7, anticorps Ring10, anticorps proteasome subunit beta 8, anticorps proteasome subunit beta 8A, anticorps proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7), anticorps PSMB8, anticorps psmb8a, anticorps Psmb8

Sujet:

Synonyms: Proteasome 20S LMP7, D6S216, D6S216E, Large multunctional peptidase 7, Large multunctional protease 7, LMP 7, LMP-7, LMP7, Low molecular mass protein 7, Low molecular weight protein 7, Macropain subunit C13, MGC1491, Multicatalytic endopeptidase complex subunit C13, Protease component C13, Proteasome prosome macropain subunit beta type 8, Proteasome prosome, macropain subunit, beta type, 8 large multunctional peptidase 7, Proteasome beta 8 subunit, Proteasome catalytic subunit 3i, Proteasome component C13, Proteasome related gene 7, Proteasome subunit beta 5i, Proteasome subunit beta type 8, Proteasome subunit beta type, Proteasome subunit beta type-8, Proteasome subunit beta-5i, Proteasome subunit Y2, PSB8_HUMAN, PSMB 8, PSMB5i, PSMB8, Really interesting new gene 10 protein, RING 10, RING10, Y2, ALDD, D6S216E, JMP, NKJO, PSMB5i, RING10.

Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified, both isoforms are processed to yield the same mature subunit. [provided by RefSeq, Jul 2008].

ID gène: 5696

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA