OXSR1 anticorps (AA 201-300) (Cy5.5)

N° du produit ABIN681813

Détail du produit anti-OXSR1 anticorps (Cy5.5)

Antigène: OXSR1 (Oxidative-Stress Responsive 1 (OXSR1))

Épitope: AA 201-300

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OXSR1 est conjugé à/à la Cy5.5

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human OXSR1.

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur OXSR1

Antigène: OXSR1 (Oxidative-Stress Responsive 1 (OXSR1))

Autre désignation: OXSR1 (OXSR1 Produits)

Synonymes: anticorps OSR1, anticorps C20orf111, anticorps HSPC207, anticorps Osr1, anticorps Perit1, anticorps dJ1183I21.1, anticorps zgc:55494, anticorps zgc:77321, anticorps OXSR1, anticorps 2210022N24Rik, anticorps 2810422B09Rik, anticorps AI462649, anticorps AW209236, anticorps mKIAA1101, anticorps odd1, anticorps osr1, anticorps wu:fb77f12, anticorps zgc:165661, anticorps oxidative stress responsive 1, anticorps oxidative stress responsive serine rich 1, anticorps oxidative stress responsive 1b, anticorps serine/threonine-protein kinase OSR1, anticorps odd-skipped related transciption factor 1, anticorps oxidative-stress responsive 1, anticorps oxidative stress responsive 1a, anticorps OXSR1, anticorps OSER1, anticorps oxsr1b, anticorps CpipJ_CPIJ015177, anticorps Tsp_00299, anticorps OSR1, anticorps Oxsr1, anticorps LOC106505565, anticorps oxsr1, anticorps oxsr1a

Sujet:

Synonyms: KIAA1101, OSR 1, OSR1, Oxidative stress responsive 1, Oxidative stress responsive 1 protein, OXSR 1, Serine/threonine protein kinase OSR1.

Background: OXSR1 is a serine/threonine kinase which regulates downstream kinases in response to environmental stress such as osmotic stresses, notably sorbitol and, to a lesser extent, NaCl. OXSR1 phosphorylated thr84 within the N-terminal regulatory domain of PAK1. Replacement of thr84 with gln reduced activation of PAK1 by an active form of the small G protein CDC42, suggesting that phosphorylation by OXSR1 modulates the G protein sensitivity of PAK. OXSR1 interacts with chloride channel proteins SLC12A6 isoform 2, SLC12A1 and SLC12A2 but not with SLC12A4 and SLC12A7, possibly establishing sensor/signaling modules that initiate the cellular response to environmental stress. Binds to and phosphorylates RELL1, RELL2 AND RELT. OXSR1 may have a role in regulating the actin cytoskeleton.

ID gène: 9943

Pathways: Tube Formation