Ephrin B anticorps (pSer300) (Cy5.5)

N° du produit ABIN684543

Détail du produit anti-Ephrin B anticorps (Cy5.5)

Antigène: Ephrin B (EphB)

Épitope: pSer300

Reactivité: Humain, Souris, Poulet, Rat, Boeuf (Vache), Chien, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ephrin B est conjugé à/à la Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Boeuf (Vache), Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human Ephrin B around the phosphorylation site of Ser300

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Ephrin B

Antigène: Ephrin B (EphB)

Abstract: EphB Produits

Sujet:

Synonyms: Ephrin B phospho Y330, p-Ephrin B phospho Y330, CEK5 ligand, EFNB1, ELK L, EphrinB, Ephrin-B, ELK ligand, ELKL, EPH related receptor tyrosine kinase ligand 2, Ephrin B Precursor, Ephrin B1, Ephrin B2, LERK 2, LERK2, EFNB2_HUMAN.

Background: Ephrin B proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development. Ephrin B molecules expressed at the membrane surface bind to the Ephrin B family receptors on target cells during cell to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing Ephrin B on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of Ephrin B is thought to be a critical component of this reverse signaling event. Recent work demonstrated that Tyr331 of Ephrin B was phosphorylated in HEK293 cells after stimulation by the soluble Ephrin B2 receptor tyrosine kinase.

ID gène: 1947