CD99 anticorps

N° du produit ABIN6934159

Détail du produit anti-CD99 anticorps

Antigène: CD99

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD99 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificité: Recognizes a sialoglycoprotein of 27-32kDa, identified as CD99, or MIC2 gene product, or E2 antigen. MIC2 gene is located in the pseudo-autosomal region of the human X and Y chromosome. MIC2 gene encodes two distinct proteins, which are produced by alternative splicing of the CD99 gene transcript and are identified as bands of 30 and 32kDa (p30/32).Although its function is not fully understood, CD99 is implicated in various cellular processes including homotypic aggregation of T cells, upregulation of T cell receptor and MHS molecules, apoptosis of immature thymocytes and leukocyte diapedesis.CD99 is expressed on the cell membrane of some lymphocytes, cortical thymocytes, and granulosa cells of the ovary. Most pancreatic islet cells, Sertoli cells of the testis, and some endothelial cells express this antigen. Mature granulocytes express very little or no CD99. MIC2 is strongly expressed on Ewing's sarcoma cells and primitive peripheral neuroectodermal tumors.

Réactivité croisée (Details): Human.

Immunogène: Human acute lymphocytic leukemia T-cells

Clone: 1-20E08

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (5-10ul/million cells); Immunofluorescence (1:50-1:100); Immunohistochemistry (Formalin-fixed) (1:50-1:100 for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined.

Positive_Control: MOLT-4 cells. Pancreas or Ewing's sarcoma.

Restrictions: For Research Use only

Stockage

Buffer: Tissue culture supernatant with 0.05% Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur CD99

Antigène: CD99

Autre désignation: CD99 (CD99 Produits)

Synonymes: anticorps 1110061M03Rik, anticorps 2410026K10Rik, anticorps D4, anticorps Pilr-l, anticorps pilr-1, anticorps HBA71, anticorps MIC2, anticorps MIC2X, anticorps MIC2Y, anticorps MSK5X, anticorps CD99 antigen, anticorps CD99 molecule (Xg blood group), anticorps CD99 molecule, anticorps Cd99, anticorps CD99

Classe de substances: Viral Protein

Sujet: 12E7; E2 antigen; MIC 2X; MIC 2Y; MIC2; Protein MIC2; Surface antigen MIC2; T-cell surface glycoprotein E2,CD99 / MIC2 (Ewing's Sarcoma Marker)
Cellular localisation: Cell surface

Poids moléculaire: 27-32kDa

ID gène: 4267, 653349

UniProt: P14209