CYP1A1/2 anticorps

N° du produit ABIN6937070

Détail du produit anti-CYP1A1/2 anticorps

Antigène: CYP1A1/2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 1/2 (CYP1A1/2))

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CYP1A1/2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificité: Cytochrome P450 oxidase (commonly abbreviated CYP) is a generic term for a large number of related, but distinct, oxidative enzymes important in vertebrate physiology. The cytochrome P450 mixed-function monooxygenase system is probably the most important element of Phase I metabolism in mammals. P450s are membrane-bound, either in the inner membrane of mitochondria or in the endoplasmic reticulum of cells where they metabolise thousands of endogenous and exogenous compounds. In the liver, these substrates include toxins, drugs, and other unneeded and potentially harmful molecules. Humans have 18 families of cytochrome P450 genes and 43 subfamilies, the CYP1 family is involved in drug metabolism and includes 3 subfamilies, 3 genes and 1 pseudogene.

Réactivité croisée (Details): Human. Mouse. Rat. Primate.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: 3-methylcholanthrene induced rat cytochrome P450 protein.

Clone: MC1

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Known_Application: Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.25-0.5 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: HeLa cells. Liver or Cardiac muscle.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur CYP1A1/2

Antigène: CYP1A1/2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 1/2 (CYP1A1/2))

Autre désignation: CYP1A1 / CYP1A2 (CYP1A1/2 Produits)

Synonymes: anticorps CP12, anticorps Cyp1a1, anticorps P450-3, anticorps cytochrome P450, family 1, subfamily a, polypeptide 2, anticorps Cyp1a2

Sujet: Aryl hydrocarbon hydroxylase, CP11, CP12, CYP1A1, CYP1A2, CYPIA1, CYPIA2, Cytochrome P450 family 1 subfamily A polypeptide 1, Cytochrome P450 family 1 subfamily A polypeptide 2, P1 450, P3 450, P450 form 4, P450 form 6, P450 P1, P450 P3,Cytochrome P450 1A1/1A2
Cellular localisation: Cytoplasmic

Poids moléculaire: 58kDa

ID gène: 1543, 1544, 437060

UniProt: P04798, P05177