CYP1A1/2 anticorps

N° du produit ABIN6939223

Détail du produit anti-CYP1A1/2 anticorps

Antigène: CYP1A1/2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 1/2 (CYP1A1/2))

Reactivité: Humain, Rat, Souris, Primate

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CYP1A1/2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Staining Methods (StM)

Purification: Purified by Protein A/G

Immunogène: 3-methylcholanthrene induced rat cytochrome P450 protein.

Clone: MC1

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: HeLa cells. Liver or Cardiac muscle.

Known Application: Immunofluorescence (0.5-1 μg/mL), Western Blot (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.25-0.5 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur CYP1A1/2

Antigène: CYP1A1/2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 1/2 (CYP1A1/2))

Autre désignation: CYP1A1 / CYP1A2 (CYP1A1/2 Produits)

Synonymes: anticorps CP12, anticorps Cyp1a1, anticorps P450-3, anticorps cytochrome P450, family 1, subfamily a, polypeptide 2, anticorps Cyp1a2

Sujet: Cytochrome P450 oxidase (commonly abbreviated CYP) is a generic term for a large number of related, but distinct, oxidative enzymes important in vertebrate physiology. The cytochrome P450 mixed-function monooxygenase system is probably the most important element of Phase I metabolism in mammals. P450s are membrane-bound, either in the inner membrane of mitochondria or in the endoplasmic reticulum of cells where they metabolise thousands of endogenous and exogenous compounds. In the liver, these substrates include toxins, drugs, and other unneeded and potentially harmful molecules. Humans have 18 families of cytochrome P450 genes and 43 subfamilies, the CYP1 family is involved in drug metabolism and includes 3 subfamilies, 3 genes and 1 pseudogene.

Poids moléculaire: 58kDa

ID gène: 1543, 1544

UniProt: P04798, P05177