HLA-DRA anticorps
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- Antigène Voir toutes HLA-DRA Anticorps
- HLA-DRA (HLA Class II DR alpha (HLA-DRA))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp HLA-DRA est non-conjugé
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Application
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificité
- This MAb reacts with the HLA-DR antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kDa alpha (heavy) chain and a 28 kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 Molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.
- Réactivité croisée (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Raji cells
- Clone
- 19-26-1-same as MB-26-1
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product HLA-DRA Anticorps primaire
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- Indications d'application
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Raji, Ramos, Daudi or HuT78 cells. Tonsil or lymph node.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- HLA-DRA (HLA Class II DR alpha (HLA-DRA))
- Autre désignation
- HLA-DRA (HLA-DRA Produits)
- Synonymes
- anticorps HLA-DRA1, anticorps MLRW, anticorps DR-alpha, anticorps HLA-DRA, anticorps Mamu-DRA1, anticorps major histocompatibility complex, class II, DR alpha L homeolog, anticorps major histocompatibility complex, class II, DR alpha, anticorps hla-dra.L, anticorps HLA-DRA, anticorps MAMU-DRA, anticorps BOLA-DRA
- Sujet
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DR alpha chain, HLA class II histocompatibility antigen, HLA class II histocompatibility antigen DR alpha chain, HLA DRA, HLA DRA1, HLA-DRA, HLADRA1, Major histocompatibility complex class II DR alpha, MHC cell surface glycoprotein, MHC class II antigen DRA,HLA-DRA (MHC II)
Cellular localisation: Cell surface - Poids moléculaire
- 36kDa (α, chain) and 27kDa (β, chain)
- ID gène
- 3122, 520048
- UniProt
- P01903
- Pathways
- TCR Signaling, CXCR4-mediated Signaling Events
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