RBP4 anticorps
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- Antigène Voir toutes RBP4 Anticorps
- RBP4 (Retinol Binding Protein 4, Plasma (RBP4))
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Reactivité
- Humain, Souris, Rat, Lapin, Singe, Chévre
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp RBP4 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Staining Methods (StM)
- Specificité
- Recognizes a protein of 21 kDa-25 kDa, identified as retinol binding protein (RBP). Its epitope localizes between aa 74-182 of human RBP. This MAb recognizes reduced and carboxy-methylated RBP (RCM-RBP) as well as the circulatory RBP but not the native RBP, thereby suggesting that its epitope becomes accessible either on unfolding or upon binding of RBP to transthyretin (prealbumin). RBP is responsible for distributing retinol from the retinoid stores in the liver to the various target tissues. Once secreted into the blood with bound retinol, the vitamin carrier circulates complexed with transthyretin prior to vitamin delivery at the plasma membrane through a receptor-mediated mechanism.
- Purification
- Purified by Protein A/G
- Immunogène
- Retinol binding protein Purified from human plasma
- Clone
- SPM442
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product RBP4 Anticorps primaire
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- Indications d'application
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Positive Control: Liver or placenta.
Known Application: Immunofluorescence (1-2 μg/mL), Western Blot (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-80 °C
- Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Date de péremption
- 24 months
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- Antigène
- RBP4 (Retinol Binding Protein 4, Plasma (RBP4))
- Autre désignation
- RBP (RBP4 Produits)
- Synonymes
- anticorps RDCCAS, anticorps RBP, anticorps RNBP, anticorps rbp4, anticorps MGC54038, anticorps srbp, anticorps PRBP, anticorps RBPA, anticorps Rbp-4, anticorps fb23c12, anticorps rbp, anticorps wu:fb23c12, anticorps wu:fb58d04, anticorps wu:fb72b04, anticorps zgc:86911, anticorps retinol binding protein 4, anticorps renin binding protein, anticorps retinol binding protein 4 S homeolog, anticorps retinol binding protein 4 A, plasma, anticorps retinol binding protein 4, plasma, anticorps retinol binding protein 4 L homeolog, anticorps RBP4, anticorps RENBP, anticorps rbp4.S, anticorps rbp4, anticorps Rbp4, anticorps RBP4A, anticorps rbp4.L
- Poids moléculaire
- 21-25kDa
- ID gène
- 5947, 5948, 5950
- UniProt
- P02753, P09455, P50120
- Pathways
- Regulatory RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response
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