AKT2 anticorps (N-Term)

N° du produit ABIN6942077

Cet anticorps anti-AKT2 Monoclonal Souris (Clone 2A1) (ABIN6942077) détecte spécifiquement AKT2 dans WB, IF, IHC (p) et IF (cc). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour AKT2 anticorps (N-Term) (ABIN6942077)

Antigène: AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp AKT2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 2A1

Détail du produit anti-AKT2 anticorps

Épitope: N-Term

Fonction: AKT2 Recombinant Antibody

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: Synthetic peptide derived from human Akt2, around N-terminal.

Isotype: IgG1

Information d'application

Indications d'application: WB(1:300-5000), IHC-P(1:200-400), IF(ICC)(1:50-200), IF()

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur AKT2

Antigène: AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))

Autre désignation: Akt2

Sujet:

Synonyms: C AKT, MGC9965, Oncogene AKT1, PKB, PRKBA, Protein Kinase B Alpha, RAC Alpha, RAC, RAC PK Alpha, RAC Serine/Threonine Protein Kinase, vAKT Murine Thymoma Viral Oncogene Homolog 1.

Background: IGF-1 leads to the activation of AKT3, which may play a role in regulating cell survival. Capable of phosphorylating several known proteins. Truncated isoform 2/PKB gamma 1 without the second serine phosphorylation site could still be stimulated but to a lesser extent. [subcellular location] Cytoplasmic and membrane-associated after cell stimulation leading to its translocation. In adult tissues, it is highly expressed in brain, lung and kidney, but weakly in heart, testis and liver. In fetal tissues, it is highly expressed in heart, liver and brain and not at all in kidney. Belongs to the Ser/Thr protein kinase family. RAC subfamily.

ID gène: 208

UniProt: P31751

Pathways: Signalisation PI3K-Akt, Signalisation RTK, AMPK Signaling, Signalisation TLR, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Hepatitis C, VEGF Signaling