DDX6 anticorps

N° du produit ABIN6942821

Détail du produit anti-DDX6 anticorps

Antigène: DDX6 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp DDX6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: Recombinant protein within human DDX6 aa 100-300

Clone: 15C2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 12 months

Détails sur DDX6

Antigène: DDX6 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6))

Autre désignation: DDX6 (DDX6 Produits)

Synonymes: anticorps si:ch211-147p17.1, anticorps P54H, anticorps Xp54, anticorps hlr2, anticorps me31b, anticorps p54, anticorps rck, anticorps HLR2, anticorps P54, anticorps RCK, anticorps p54h, anticorps RGD1564560, anticorps 1110001P04Rik, anticorps E230023J21Rik, anticorps mRCK/P54, anticorps DEAD-box helicase 6, anticorps DEAD (Asp-Glu-Ala-Asp) box helicase 6, anticorps DEAD-box helicase 6 L homeolog, anticorps DEAD (Asp-Glu-Ala-Asp) box polypeptide 6, anticorps DDX6, anticorps ddx6, anticorps ddx6.L, anticorps Ddx6

Sujet:

Synonyms: Probable ATP-dependent RNA helicase DDX6, ATP-dependent RNA helicase p54, DEAD box protein 6, Oncogene RCK, DDX6, HLR2, RCK.

Background: RCK, also known as DDX6 and P54, is a member of the DEAD-box RNA helicase family of proteins, all of which share common protein motifs. Found in most tissues, RCK is an unwindase that exhibits ATP-dependent RNA un-winding activity, as well as the ability to decay RNA in the 5'-3' direction. In non-malignant cells, RCK is associated with all processes of normal RNA metabolism including splicing, export and translation initiation. Mutations in the gene encoding RCK can cause the protein to be overexpressed, changing its function to that of an oncogene that positively regulates the expression of genes involved in cell growth and proliferation. It is believed that, through its unwindase activity, the main function of RCK is to downregulate mRNA expression and maintain normal transcriptional levels within the cell.

ID gène: 1656

UniProt: P26196

Pathways: Ribonucleoprotein Complex Subunit Organization