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Envoplakin-Like anticorps (AA 101-200) (Cy5)

EVPLL Reactivité: Humain IF (cc), IF (p) Hôte: Lapin Polyclonal Cy5
N° du produit ABIN6943324
  • Antigène Tous les produits Envoplakin-Like (EVPLL)
    Envoplakin-Like (EVPLL)
    Épitope
    • 14
    • 7
    • 7
    • 6
    • 6
    • 1
    • 1
    AA 101-200
    Reactivité
    Humain
    Hôte
    • 29
    Lapin
    Clonalité
    • 29
    Polyclonal
    Conjugué
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Envoplakin-Like est conjugé à/à la Cy5
    Application
    • 15
    • 15
    • 12
    • 12
    • 12
    • 5
    • 3
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human EVPLL
    Isotype
    IgG
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Envoplakin-Like (EVPLL)
    Autre désignation
    EVPLL (EVPLL Produits)
    Synonymes
    anticorps envoplakin like, anticorps EVPLL
    Sujet

    Synonyms: Envoplakin like, Envoplakin-like protein, EVPLL, EVPLL_HUMAN,

    Background: EVPLL (envoplakin-like protein) is a 301 amino acid protein that belongs to the plakin or cytolinker family. The gene encoding EVPLL maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

    ID gène
    645027
    UniProt
    A8MZ36
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