PDIA6 anticorps

N° du produit ABIN6944473

Détail du produit anti-PDIA6 anticorps

Antigène: PDIA6 (Protein Disulfide Isomerase Family A, Member 6 (PDIA6))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp PDIA6 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: Human PDIA6 between 300 to 500 amino acids

Clone: 4C3

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
FCM 1:20-100
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur PDIA6

Antigène: PDIA6 (Protein Disulfide Isomerase Family A, Member 6 (PDIA6))

Autre désignation: PDIA6 (PDIA6 Produits)

Synonymes: anticorps 1700015E05Rik, anticorps AL023058, anticorps C77895, anticorps CaBP5, anticorps P5, anticorps Txndc7, anticorps ERP5, anticorps TXNDC7, anticorps CaBP1, anticorps pdi-p5, anticorps erp5, anticorps pdia6, anticorps pdip5, anticorps txndc7, anticorps protein disulfide isomerase family A member 6, anticorps protein disulfide isomerase associated 6, anticorps protein disulfide isomerase family A, member 6, anticorps protein disulfide isomerase family A member 6 L homeolog, anticorps PDIA6, anticorps Pdia6, anticorps pdia6.L

Sujet:

Synonyms: Protein disulfide-isomerase A6, Endoplasmic reticulum protein 5, Protein disulfide isomerase P5, Thioredoxin domain-containing protein 7, ER protein 5, ERp5, PDIA6

Background: May function as a chaperone that inhibits aggregation of misfolded proteins (PubMed:12204115). Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling (PubMed:24508390). May also regulate the UPR via the EIF2AK3 UPR sensor (PubMed:24508390). Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin (PubMed:15466936).

ID gène: 10130

UniProt: Q15084

Pathways: ER-Nucleus Signaling, Cell RedoxHomeostasis