SARS-CoV-2 Spike anticorps

N° du produit ABIN6952492

Détail du produit anti-SARS-CoV-2 Spike anticorps

Antigène: SARS-CoV-2 Spike

Reactivité: SARS Coronavirus-2 (SARS-CoV-2)

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp SARS-CoV-2 Spike est non-conjugé

Application: Veuillez nous consulter SVP

Clone: 5D9

Information d'application

Restrictions: For Research Use only

Stockage

Buffer: Supplied as a 0.2 um filtered solution of PBS, pH 7.4

Stock: -20 °C

Stockage commentaire: Store at -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.

Détails sur SARS-CoV-2 Spike

Antigène: SARS-CoV-2 Spike

Abstract: SARS-CoV-2 Spike Produits

Synonymes: anticorps E2, anticorps E2 glycoprotein precursor, anticorps Surface Glycoprotein, anticorps S

Classe de substances: Viral Protein

Sujet: Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

ID gène: 43740568

UniProt: P0DTC2