TNF alpha anticorps

N° du produit ABIN6963896

Cet anticorps Rat Monoclonal détecte spécifiquement TNF alpha dans ELISA et ELISpot. Il présente une réactivité envers Souris et a été mentionné dans 5+ publications.

Aperçu rapide pour TNF alpha anticorps (ABIN6963896)

Antigène: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp TNF alpha est non-conjugé

Application: ELISA, ELISpot

Clone: MT1C8-23C9

Détail du produit anti-TNF alpha anticorps

Specificité: Native and recombinant TNF-α

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Stérilité: 0.2 μm filtered

Immunogène: Recombinant mouse TNF-alpha

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Date de péremption: 18 months

Références pour anticorps anti-TNF alpha (ABIN6963896)

Chen, Chen, Ren, Xia, Zhu, Liu, Zhang, Tang, Sun, Liu, Dong: "Aberrant DNA methylation of mTOR pathway genes promotes inflammatory activation of immune cells in diabetic kidney disease." dans: Kidney international, Vol. 96, Issue 2, pp. 409-420, (2020) (PubMed).

Li, Yan, Huang, Chi, Xu, Li, Liu, Feng, Wang, Zhao, Yang, Xia: "Characterization of the Immune Response of MERS-CoV Vaccine Candidates Derived from Two Different Vectors in Mice." dans: Viruses, Vol. 12, Issue 1, (2020) (PubMed).

Li, Chi, Huang, Yan, Zhang, Liu, Wang, Li, Zhang, Mo, Jin, Wang, Feng, Wang, Bi, Wang, Sun, Gao, Zhao, Yang, Xia: "A Novel Bacterium-Like Particle Vaccine Displaying the MERS-CoV Receptor-Binding Domain Induces Specific Mucosal and Systemic Immune Responses in Mice." dans: Viruses, Vol. 11, Issue 9, (2020) (PubMed).

Chida, Hara, Yano, Uchiyama, Das, Takahashi, Miyata, Tomioka, Ito, Kido, Sakaguchi: "Prion protein protects mice from lethal infection with influenza A viruses." dans: PLoS pathogens, Vol. 14, Issue 5, pp. e1007049, (2018) (PubMed).

Abbassi-Daloii, Yousefi, Sekhavati, Tahmoorespur: "Impact of heat shock protein 60KD in combination with outer membrane proteins on immune response against Brucella melitensis." dans: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, Vol. 126, Issue 1, pp. 65-75, (2018) (PubMed).

Détails sur TNF alpha

Antigène: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Autre désignation: TNFA

ID gène: 21926

Pathways: Signalisation NF-kappaB, Apoptose, Caspase Cascade in Apoptosis, Signalisation TLR, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome