MYST1 anticorps (AA 351-450) (AbBy Fluor® 350)

N° du produit ABIN6976403

Détail du produit anti-MYST1 anticorps (AbBy Fluor® 350)

Antigène: MYST1 (KAT8) (K(lysine) Acetyltransferase 8 (KAT8))

Épitope: AA 351-450

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYST1 est conjugé à/à la AbBy Fluor® 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris

Homologie: Rat,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MYST1/KAT8

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur MYST1

Antigène: MYST1 (KAT8) (K(lysine) Acetyltransferase 8 (KAT8))

Autre désignation: MYST1/KAT8 (KAT8 Produits)

Synonymes: anticorps myst1, anticorps wu:fb22g02, anticorps wu:fj22d09, anticorps zgc:66387, anticorps Myst1, anticorps MOF, anticorps MYST1, anticorps ZC2HC8, anticorps hMOF, anticorps 2010203C02Rik, anticorps 5830450F21Rik, anticorps D7Ertd629e, anticorps K(lysine) acetyltransferase 8, anticorps lysine acetyltransferase 8, anticorps kat8, anticorps KAT8, anticorps Kat8

Sujet:

Synonyms: EC 2.3.1.48, Histone acetyltransferase KAT8, Histone acetyltransferase MYST1, hMOF, K(lysine) acetyltransferase 8, KAT 8, Lysine acetyltransferase 8, MOF, MOZ, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1, MYST 1, MYST histone acetyltransferase 1, myst protein 1, MYST-1, MYST1, MYST1_HUMAN, Ortholog of Drosophila males absent on the first (MOF), Probable histone acetyltransferase MYST1, SAS2 and TIP60 protein 1, SAS2, SAS3, TIP60 protein 1, YBF2, YBF2/SAS3.

Background: Dosage compensation ensures that males with a single X chromosome and females with two X chromosomes have the same amount of most X-linked gene products. In Drosophila, this is acheived by enhancing the level of transcription of the X chromosome in males. Proteins such as maleless, male specific lethal 1, 2 and 3, and males absent on the first (MOF) form a dosage compensation complex (DCC) that is required for the twofold increase of transcription of the male X chromosome. The DCC is preferentially associated with many sites on the X chromosome in somatic cells of males. The binding of the DCC to the X chromosome is dependent upon histone 4 acetylation at lysine 16, which is accomplished by MOF. In mammals, MOF (also designated hMOF, MYST1, or MOZ) belongs to the MYST family of histone acetyl transferases which are characterized by a unique C2HC-type zinc finger close to their HAT domains. MOF utilizes the zinc finger domain to contact the globular part of the nucleosome as well as the histone H4 N-terminal tail substrate. The carboxy terminal domain of human MOF also has histone acetyltransferase activity directed against histones H3 and H2A, a characteristic shared with other MYST family histone acetyltransferases.

ID gène: 84148

UniProt: Q9H7Z6