COPG1, COPG2 (AA 1-100) anticorps (Cy5)

N° du produit ABIN6984171

Détail du produit

Antigène: COPG1, COPG2

Épitope: AA 1-100

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Cow

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human COPG2

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: COPG1, COPG2

Autre désignation: COPG1 + COPG2

Sujet:

Synonyms: 2 COP, Coat protein nonclathrin gamma 2 cop, Coatomer protein complex subunit gamma 2, Coatomer subunit gamma 2, Coatomer subunit gamma-2, COPG 2, Copg2, COPG2_HUMAN, DKFZp761N09121, FLJ11781, Gamma 2 coat protein, Gamma 2 COP, Gamma-2-coat protein, Gamma-2-COP, Coatomer subunit gamma-1, COPG1, Gamma-1-coat protein, Gamma-1-COP, COPG

Background: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.

ID gène: 22820, 26958

UniProt: Q9Y678, Q9UBF2