GOT2 anticorps

N° du produit ABIN6989684

Détail du produit anti-GOT2 anticorps

Antigène: GOT2 (Glutamic-Oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2) (GOT2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp GOT2 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: Synthetic Peptide within Human GOT2.

Clone: 4H6

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur GOT2

Antigène: GOT2 (Glutamic-Oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2) (GOT2))

Autre désignation: GOT2 (GOT2 Produits)

Synonymes: anticorps KAT4, anticorps KATIV, anticorps mitAAT, anticorps AI789014, anticorps Got-1, anticorps cAspAT, anticorps cCAT, anticorps AL022787, anticorps FABP-pm, anticorps Got-2, anticorps mAspAT, anticorps ASPATA, anticorps got2, anticorps zgc:66329, anticorps fj40h07, anticorps wu:fj40h07, anticorps zgc:56425, anticorps glutamic-oxaloacetic transaminase 2, anticorps glutamic-oxaloacetic transaminase 1, soluble, anticorps glutamatic-oxaloacetic transaminase 2, mitochondrial, anticorps glutamic-oxaloacetic transaminase 2a, mitochondrial, anticorps glutamic-oxaloacetic transaminase 2 L homeolog, anticorps Aspartate amino transferase activity, anticorps glutamic-oxaloacetic transaminase 2b, mitochondrial, anticorps GOT2, anticorps got2, anticorps Got1, anticorps Got2, anticorps got2a, anticorps got2.L, anticorps AST, anticorps got2b

Sujet:

Synonyms: AATM_HUMAN antibody, AL022787 antibody, Aspartate aminotransferase 2 antibody, Aspartate aminotransferase antibody, Aspartate aminotransferase, mitochondrial antibody, Aspartate transaminase 2 antibody, ASPATA antibody, EC 2.6.1.1 antibody, FABP 1 antibody,

Background: GOT2 [Glutamate oxaloacetate transaminase] is a ubiquitous pyridoxal phosphate dependent enzyme which exists in both mitochondrial and cytosolic forms. The enzyme plays an important role in amino acid metabolism and in the urea and tricarboxylic acid cycles. The 2 isoenzymes are homodimeric. In liver about 80 % of the enzyme activity is mitochondrial in origin, whereas in serum the enzyme activity is largely cytosolic. Although the mitochondrial and soluble forms of GOT are coded by different chromosomes, the 2 show close homology in amino acid sequence and were presumably derived from a common ancestral gene. Serum GOT [with SGPT] levels are usually elevated in states of hepatocellular injury (injury to the liver cells), the highest levels are associated with hepatitis of a viral origin. High levels are also found after myocardial infarction, when SGPT levels are lower.

ID gène: 2806

UniProt: P00505

Pathways: Monocarboxylic Acid Catabolic Process