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MEK1 anticorps (pSer218, pSer222)

Cet anticorps anti-MEK1 est un anticorps Lapin Monoclonal détectant MEK1 dans WB, IHC, IHC (p), IP, IF (cc) et FACS. Adapté pour Humain et Souris.
N° du produit ABIN6989931

Aperçu rapide pour MEK1 anticorps (pSer218, pSer222) (ABIN6989931)

Antigène

Voir toutes MEK1 (MAP2K1) Anticorps
MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))

Reactivité

  • 334
  • 183
  • 177
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Humain, Souris

Hôte

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  • 31
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  • 2
Lapin

Clonalité

  • 267
  • 72
Monoclonal

Conjugué

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Cet anticorp MEK1 est non-conjugé

Application

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Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunofluorescence (Cultured Cells) (IF (cc)), Flow Cytometry (FACS)

Clone

3B1
  • Épitope

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    pSer218, pSer222

     Réactivité croisée

    Humain, Souris

    Purification

    Purified by Protein A.

    Immunogène

    Synthetic phospho-Peptide corresponding to residues surrounding Ser218 and 222 of human MEK1.

    Isotype

    IgG
  • Indications d'application

    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    IP(1-2 μg)
    IHC()

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C for 12 months.

    Date de péremption

    12 months
  • Antigène

    MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))

    Autre désignation

    MEK1

    Sujet

    Synonyms: Dual specificity mitogen activated protein kinase kinase 1 antibody, Dual specificity mitogen-activated protein kinase kinase 1 antibody, ERK activator kinase 1 antibody, MAP kinase kinase 1 antibody, MAP kinase/Erk kinase 1 antibody, MAP2K1 antibody, MAPK/ERK kinase 1 antibody, MAPKK 1 antibody, MAPKK1 antibody, MEK 1 antibody, Mek1 antibody, MEKK1 antibody, Mitogen activated protein kinase kinase 1 antibody, MKK 1 antibody, MKK1 antibody, MP2K1_HUMAN antibody, PRKMK1 antibody, Protein kinase mitogen activated kinase 1 (MAP kinase kinase 1) antibody, Protein kinase mitogen activated, kinase 1 antibody, hide

    Background: The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.

    ID gène

    5604

    UniProt

    Q02750

    Pathways

    Signalisation MAPK, Signalisation RTK, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
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