TNFSF13 anticorps (Extracellular Domain)

N° du produit ABIN6990366

Détail du produit anti-TNFSF13 anticorps

Antigène: TNFSF13 (Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13))

Épitope: AA 180-230, Extracellular Domain

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNFSF13 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: APRIL Antibody is affinity chromatography purified via peptide column.

Immunogène: APRIL antibody was raised against a synthetic peptide corresponding to amino acids within a extracellular domain of human APRIL. The immunogen is located within amino acids 180 - 230 of APRIL.

Isotype: IgG

Information d'application

Indications d'application: APRIL antibody can be used for detection of APRIL by Western blot at 1 - 4 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: APRIL Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: APRIL antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur TNFSF13

Antigène: TNFSF13 (Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13))

Autre désignation: APRIL (TNFSF13 Produits)

Synonymes: anticorps APRIL, anticorps CD256, anticorps TALL-2, anticorps TALL2, anticorps TRDL-1, anticorps ZTNF2, anticorps 2310026N09Rik, anticorps April, anticorps Tall2, anticorps Trdl1, anticorps SLAN, anticorps ANP32B, anticorps april, anticorps tnf13, anticorps TNLG7B, anticorps TNF superfamily member 13, anticorps tumor necrosis factor (ligand) superfamily, member 13, anticorps acidic leucine-rich nuclear phosphoprotein 32 family member B, anticorps TNFSF13, anticorps Tnfsf13, anticorps LOC494442, anticorps tnfsf13

Sujet: APRIL Antibody: Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for a proliferation-inducing ligand), TALL-2 (for TNF- and ApoL-related Leukocyte-expressed Ligand 2), and TRDL-1α, (for TNF related death ligand 1α,) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-κ,B, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer.

Poids moléculaire: Predicted: 27 kDa

Observed: 27 kDa

ID gène: 8741

NCBI Accession: NP_003799

UniProt: O75888

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response