TNFSF15 anticorps (N-Term)

N° du produit ABIN6990418

Détail du produit anti-TNFSF15 anticorps

Antigène: TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))

Épitope: AA 60-110, N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNFSF15 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: This polyclonal antibody will not cross-react with TL1.

Purification: TL1A Antibody is affinity chromatography purified via peptide column.

Immunogène: TL1A antibody was raised against a peptide corresponding to 14 amino acids near the amino terminus of human TL1A. The immunogen is located within amino acids 60 - 110 of TL1A.

Isotype: IgG

Information d'application

Indications d'application: TL1A antibody can be used for detection of TL1A by Western blot at 0.5 to 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TL1A Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: TL1A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur TNFSF15

Antigène: TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))

Autre désignation: TL1A (TNFSF15 Produits)

Synonymes: anticorps TTPAL, anticorps TL1, anticorps TL1A, anticorps VEGI, anticorps VEGI192A, anticorps Tl1, anticorps Tl1a, anticorps Vegi, anticorps tumor necrosis factor superfamily member 15, anticorps TNF superfamily member 15, anticorps tumor necrosis factor (ligand) superfamily, member 15, anticorps TNFSF15, anticorps Tnfsf15

Sujet: TL1A Antibody: Members in the TNF and its receptor superfamilies regulate immune responses and induce apoptosis. DR3 (also termed Wsl-1, Apo-3, TRAMP, and LARD) is preferentially expressed by T lymphocytes and upregulated during T cell activation. The ligand for DR3 was recently identified and designated TL1A. TL1A also binds decoy receptor DcR3/TR6, which is expressed in several lung and colon carcinomas and in some normal tissues. TL1A induces apoptosis and NF-κ,B activation in DR3 expressing cells, which is antagonized by DcR3. TL1A is upregulated by proinflammatory cytokines TNF and IL-1. TL1A is a longer variant of TL1 (also called VEGI).

Poids moléculaire: Predicted: 28 kDa

Observed: 26 kDa

ID gène: 9966

UniProt: O95150

Pathways: Positive Regulation of Endopeptidase Activity, Autophagy